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Newsletter August 2023

Welcome to your go-to source for all things wellness-related. In this newsletter, we explore the fascinating world of wellness and alternative medicine, with a special focus on psychedelics, CBD, nootropics, and functional mushrooms.


Whether you're a curious newcomer or a seasoned veteran, you'll find something of interest in each issue of the Amsterdam Wellness Insider. So sit back, relax, and join us on this exciting journey into the cutting-edge world of wellness.


The When Nature Calls Team



What Was the Tipping Point for the Psychedelic Renaissance?

In the world of scientific research, there are moments that ignite transformative change, shaping entire fields of study. For the realm of psychedelics, such a pivotal moment came in 2006, when a groundbreaking study conducted by researchers at Johns Hopkins University shed new light on the potential of psilocybin, a naturally occurring psychedelic compound found in certain mushrooms and truffles. This study's findings served as the tipping point for the psychedelic renaissance, reawakening interest in this unique class of substances and inspiring a wave of research with profound implications for mental health and consciousness exploration.


The Landmark Study: The study, titled "Psilocybin Can Occasion Mystical-Type Experiences Having Substantial and Sustained Personal Meaning and Spiritual Significance," was published in the journal Psychopharmacology. Led by a team of researchers at the Center for Psychedelic and Consciousness Research at Johns Hopkins, the study sought to investigate the effects of psilocybin on healthy volunteers.


The researchers administered psilocybin to the participants in a controlled, supportive environment. What they discovered was nothing short of remarkable. The study revealed that the participants experienced profound mystical-type experiences characterized by feelings of unity, transcendence, and a sense of interconnectedness with the universe.


The study's findings were not only remarkable for their scientific insights but also for their impact on the perception of psychedelics. The positive and transformative nature of the experiences reported by participants challenged the prevailing stigma and misperceptions surrounding these compounds, which had led to their prohibition decades earlier. This publication in 2006 marked a turning point for psychedelic research, serving as a catalyst for change that captured the attention of scientists, clinicians, and the public alike. It sparked a renewed interest in studying these substances and exploring their potential therapeutic applications for various mental health conditions, such as depression, anxiety, PTSD, addiction, and end-of-life distress, setting in motion a wave of research and clinical investigations.


Since 2006, the Center for Psychedelic and Consciousness Research at Johns Hopkins,  continues to lead the way in exploring the therapeutic potential of psychedelics. The center is currently working on studies with psilocybin’s effect on a wide array of conditions (for a taster see below). As we stand at the cusp of a new era of psychedelic science, we are reminded of the power of scientific inquiry, empathy, and innovation to shape a new era of transformative mental health care.



Why we are encouraging people to stop microdosing

Microdosing, the practice of taking sub-perceptual doses of psychedelic substances like psilocybin, has gained popularity for its potential cognitive and emotional benefits. However, it's crucial to understand that sustained microdosing without breaks can lead to diminishing effects. In this article, we emphasise the significance of tolerance and the need to take breaks from microdosing for an optimal and sustainable experience.


Microdosing involves taking a fraction of a regular dose, typically around 1/10th, to avoid any significant psychedelic effects. This method allows users to experience sub-perceptual benefits without disrupting their daily activities. The brain and body quickly build a tolerance to psilocybin with continuous use. As a result, microdosing loses its effectiveness over time, requiring higher doses for the same effects. To maintain the benefits of microdosing, it's essential to reset tolerance regularly.


We encourage users to take a two-week break after eight weeks of microdosing (according to the Fadiman protocol, to learn more on that click here). This break period allows the body to reset its tolerance, ensuring that smaller doses remain effective. Continuously microdosing without breaks can lead to diminishing returns, as users may experience reduced effects and feel the need to increase their dosage frequently. Taking breaks helps avoid this scenario, making microdosing more sustainable and effective.


It's important for individuals to monitor their tolerance levels during microdosing. If the effects seem less pronounced, it may indicate the need for a break. However, it can often be confused with finding the right dosage. Experimenting with different dosing protocols and dosage amount is crucial to finding a "sweet spot" that works best for each individual.


During the break period of microdosing, it's helpful to understand that there are no withdrawal effects to be concerned about. On the contrary, this downtime can offer valuable opportunities to reflect and continue experiencing the benefits of microdosing. Taking a break allows the body to reset its tolerance, ensuring that the positive effects of microdosing can still be felt and appreciated when resuming the practice. Moreover, this time off provides a fantastic opportunity to reassess personal goals and intentions. It's a chance to reflect on the insights gained during the microdosing journey, reevaluate priorities, and set new intentions for the upcoming microdosing cycles. Embracing these break periods with intention and mindfulness can contribute to a more meaningful and transformative microdosing experience in the long run.

To learn more about our microdosing click here.


Why are people putting mushrooms on their face?

(Special discount code at end of article)

As the wellness sector continues to evolve, a new trend is taking the skincare world by storm - functional mushrooms. These natural wonders, renowned for their numerous health benefits, are now making their way into skincare products. In this article, we'll explore why functional mushrooms are becoming a sensation in the beauty industry, shedding light on their potential benefits for skin health. 


The use of functional mushrooms in skincare products is steadily gaining popularity, thanks to their rich reservoir of antioxidants, glucans, and polysaccharides. Cultures worldwide have used these natural wonders for thousands of years, and their effectiveness in fighting anti-aging and pigmentation is drawing modern consumers towards them.



One prime example of the mushroom skincare revolution is "The Shroom Essence." This product utilizes fermented mushrooms like cordyceps, chaga, and reishi, along with CBD, PHA, and hyaluronic acid. This potent essence offers multi-depth hydration, moisture retention, and an antioxidant boost, leaving skin rejuvenated, plumped, and smooth.


Beyond topical products like "The Shroom Essence," functional mushrooms like snow fungus, reishi, and cordyceps can also be ingested to promote skin health. Healthy skin starts from the inside out, and incorporating these mushrooms into one's diet can support gut health and reduce stress, positively impacting skin conditions.


One of the most appealing aspects of functional mushrooms for skincare is their all-natural composition. Polysaccharides in mushrooms like snow fungus and reishi moisturize the skin, while beta-glucans in reishi and shiitake soothe irritation and reduce redness. Triterpenoids in reishi promote collagen production, vitamins and minerals nourish the skin, and ergothioneine neutralizes free radicals. Additionally, adaptogens in reishi and chaga help combat environmental stress, enhancing overall skin health and resilience.


Functional mushrooms have shown promise in addressing various skincare concerns, including reducing redness from rosacea, minimizing large pores, brightening dull skin, soothing acne, and de-puffing swollen areas.


Integrating functional mushrooms into skincare routines has never been easier. While topical creams exist, there are also capsulespowders for lattes or tea, or even tinctures.


As functional mushrooms continue to make their mark in skincare, it's evident that their potential benefits are garnering attention. However, it's essential to approach mushroom-based skincare with informed decision-making and a focus on natural, gentle, and effective formulations. While mushroom-based skincare products offer exciting potential, individual results may vary. Patience is crucial, as results may not be immediate. It's vital to choose reputable brands and verify the source and potency of the mushrooms used. By understanding the unique advantages of functional mushrooms and considering their inclusion in skincare routines, you can unlock the wonders of nature for healthy, radiant skin. As with any skincare journey, embracing innovation and trends is empowering, but it's also essential to prioritize personal well-being and individual skin needs.

 Get 10% off The Shroom Essence and ALL Functional mushroom products with the code: SKINCARE_AUGUST


Brand Spotlight: Sitre

intimacy and inclusivity


In celebration of Amsterdam Pride Week, we are thrilled to shine a spotlight on Sitre, an empowering brand born in Denmark with a mission to revolutionize the world of intimacy. Founded by Cecilie Hjelmager and Julie Herskin, Sitre emerged from a genuine need for a more honest, inclusive, and caring approach to intimacy, crafting products and sharing stories that resonate with people of all sexualities, ages, genders, and bodies.

At the heart of Sitre's philosophy lies a deep commitment to pleasure and intimacy, recognizing their profound impact on our lives. With a firm belief that intimacy deserves the utmost respect, Sitre crafts high-quality products and shares authentic narratives to transform the way we perceive and experience pleasure.

To learn more about their product range, click here.



Our favourite podcasts this month  


Discover our favorite podcasts of the month, where we delve into fascinating topics ranging from wellness and personal growth to the latest trends in the world of functional mushrooms and psychedelic research. Tune in and expand your horizons with these thought-provoking conversations.


An interesting discussion on a classic buddhist list called the four foundations of mindfulness which lays out various techniques for developing mindfulness

Guest Robert Malenka MD, PhD, a profesor of psychiatry and behavioural sciences at Stanford School of Medicine, discusses the brain reward circuits and how they drive our choices

Do you really need 8 hours of sleep? This episode Dr. Jen digs into the pop culture's focus on "how to sleep"- its time to debunk some common myths

Cordyceps 101, this podcast delves into the wonders of Cordyceps 

The science of happiness with Laurie Santos. Learn some surprising findings on what and what doesn't make us happy.