Psilocybin

A naturally occurring psychedelic compound that profoundly alters perception, cognition, and emotional processing.

BOTANICAL INFORMATION

• Scientific Name: Psilocybin
• Source Organism: Psilocybe species (e.g. Psilocybe cubensis)
• Family: Hymenogastraceae
• Native Regions: Global (tropical and temperate regions)

ACTIVE COMPOUNDS

• Psilocybin → converted to psilocin (active form)

Acts primarily on:

• Serotonin receptors (5-HT2A)

TRADITIONAL USES AND BENEFITS

• Traditional Uses:
  Used for centuries in Mesoamerican rituals for healing, divination, and spiritual insight
• Potential Benefits (clinical research context):
  • Reduces depression and anxiety (especially treatment-resistant cases)
  • Facilitates emotional processing and trauma work
  • Increases openness and psychological flexibility
  • Can produce lasting perspective shifts
  • Enhances sense of meaning and connection

PREPARATION & DOSAGE

• Methods of Use:
  • Dried mushrooms
  • Capsules (microdosing)
  • Extracts
• Dosage (general ranges):
  • Microdose: ~0.1–0.3 g dried
  • Moderate: ~1–2 g
  • High: 3 g+

ADDITIONAL NOTES

• Effects vary significantly by individual and setting
• Effects are highly dependent on set & setting
• Not physically addictive, but psychologically intense
• Can induce both positive and challenging experiences
• Integration (after experience) is critical